These DNA techniques are also extremely powerful for measuring ancestral lineage markers in human populations. Ancestral lineage markers are passed down from generation to generation without change, except for rare mutational events. There are two principal types of ancestral lineage markers, paternal and maternal. Paternal lineage markers are located on the Y chromosome, while maternal lineage markers are found in mitochondrial DNA.
The lack of recombination within the Y chromosome has resulted in the chronological accumulation ancient DNA point mutations, or single nucleotide polymorphisms (SNPs), that are associated with population development and the peopling of the world. The entire male population can be classified into 20 major haplogroups; A through T. Additional mutations within each of the major haplogroups further define subclades that typically illustrate more localized distribution reflecting recent human migrations.
Coming out of Africa, it is believed that man initially followed a southern coastal route, exiting Africa at either the southern or northern section of the Arabian Peninsula, hugging the shoreline out around what today is India and reaching as far as Australia some 40-60,000 years ago. However, the Bradshaw Foundation places the early eastern migrational path from Africa across the mouth of the Red Sea approximately 20,000 years earlier. If accurate, it would place Homo sapiens into the east coast of Asia prior to the eruption of Mt. Toba, 74,000 years ago, isolating a population of individuals far from our earliest genetic ancestor thousands of years before his birth.